Table S1 - Numerical and Structural Genomic Aberrations Are Reliably Detectable in Tissue Microarrays of Formalin-Fixed Paraffin-Embedded Tumor Samples by Fluorescence In-Situ Hybridization

Detailed results of all experiments performed within the entire study cohort consisting of DLBCL, FL and MM specimens. The numbers of cases studied and the individual in samples with chromosome banding data available, the FISH-probes used for the detection of either structural or numerical genomic aberrations, the number of cases investigated by either TMA-FISH or FISH of whole tissue sections and the number of cases additionally analyzed by qPCR are given. FISH results are provided as numbers of positive cells in [%], if aberrant, while qPCR results indicating genetic deletion are provided as ‘loss’. Abbrevations: DLBCL: Diffuse large B-cell lymphoma; FL: Follicular lymphoma; BAP: Break-apart probe; LSI: locus-specific identifier; Chr.: chromosome; WTS: whole tissue section; qPCR: quantitative real-time PCR on the DNA-level; Karyotypic abbreviations: der: derivative; del: deleted; bidel: biallelic deletion; dup: duplicated; add: added. (XLSX)本研究队列纳入了弥漫性大B细胞淋巴瘤（Diffuse Large B-Cell Lymphoma, DLBCL）、滤泡性淋巴瘤（Follicular Lymphoma, FL）及多发性骨髓瘤（Multiple Myeloma, MM）标本，本文件完整呈现了该队列内所有实验的详细结果。文中列出了本次研究的总病例数、具备染色体显带数据的样本例数、用于检测结构性或数量性基因组畸变的荧光原位杂交（Fluorescence In Situ Hybridization, FISH）探针类型、采用组织微阵列-FISH（TMA-FISH）或全组织切片FISH检测的病例数，以及额外通过定量实时聚合酶链反应（quantitative real-time PCR, qPCR）分析的病例数。若检测到基因组畸变，FISH结果以异常阳性细胞占比（%）形式给出；而提示基因缺失的qPCR结果则以"loss"标注。缩写注释如下：DLBCL：弥漫性大B细胞淋巴瘤；FL：滤泡性淋巴瘤；BAP：断裂分离探针（Break-apart Probe）；LSI：位点特异性标识符（Locus-specific Identifier）；Chr.：染色体（Chromosome）；WTS：全组织切片（Whole Tissue Section）；qPCR：DNA水平定量实时聚合酶链反应（quantitative real-time PCR）；核型缩写：der：衍生染色体（derivative）；del：缺失（deleted）；bidel：双等位基因缺失（biallelic deletion）；dup：重复（duplicated）；add：附加（added）。本数据集文件格式为XLSX。