Intra- and inter-modular effects of mutations.

The first row corresponds to the normalized phenotypic effect of a genetic mutation on its own module; the second row corresponds to the normalized phenotypic effect of a genetic mutation within a module on the other modules (pleiotropy). The median��SE are presented for FG and MVG, p-value is as obtained from Wilcoxon rank sum test for equal medians. The range of effects in solution space was obtained by measuring the effects over a large random sample of genomes that solve G1 (see Text S1 section 3).第一行代表单个基因突变对其所在模块的标准化表型效应；第二行代表模块内基因突变对其他模块的标准化表型效应（即多效性（pleiotropy））。FG与MVG均以中位数±标准误（SE）的形式呈现，用于检验两组中位数相等的p值由威尔科克森秩和检验计算得到。解空间中的效应值范围通过对大量求解G1的基因组随机样本进行效应值测量获得，详见补充材料S1第3节。