Mutation rates and sequencing data for pol2-M644G ± MSH2 strains.

Some 5-FOA resistant mutants had no sequence change in the 804 base pair URA3 open reading frame. These mutants were not investigated further, but they may result from epigenetic silencing, they may contain sequence changes in the promoter or 3′ untranslated region of URA3, or they may contain mutations in other genes that result in 5-FOA resistance.aExpanded from [21].bExpanded from [13].