Mutation rates and sequencing data for pol2-M644G ± MSH2 strains.

Some 5-FOA resistant mutants had no sequence change in the 804 base pair URA3 open reading frame. These mutants were not investigated further, but they may result from epigenetic silencing, they may contain sequence changes in the promoter or 3′ untranslated region of URA3, or they may contain mutations in other genes that result in 5-FOA resistance.aExpanded from [21].bExpanded from [13].部分抗5-氟乳清酸（5-FOA）突变体在804碱基对（base pair）长的URA3开放阅读框（open reading frame）中未检测到序列变化。此类突变体未被进一步研究，但其产生原因可能为表观遗传沉默，或是在URA3的启动子或3'非翻译区（3′ untranslated region）存在序列改变，亦或是携带其他可引发5-FOA抗性的基因突变。a 改编自文献[21]；b 改编自文献[13]。