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Organocatalyzed Asymmetric Synthesis of Dihydrodibenzofurans Based on a Dienamine Process

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NIAID Data Ecosystem2026-03-07 收录
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The first organocatalyzed asymmetric method for the synthesis of dihydrodibenzofurans based on a dienamine process has been developed. This two-step protocol works with a broad range of substrates and delivers only the cis-diastereomer in good yield with up to 91% ee. The enantioenriched products have been transformed to highly functionalized and partially hydrogenated dibenzofurans in excellent diastereoselectivities.

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2016-02-18
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