A novel catalytic asymmetric Michael addition of azomethine ylide with β-substituted alkylidene bisphosphates was realized in the presence of a chiral copper(I)/TF-BiphamPhos complex. The present syst
Crystal structure of human FPPS in complex with ibandronate Descriptor: Farnesyl Diphosphate Synthase, IBANDRONATE, PHOSPHATE ION, ... Authors: Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig
Introduction: Bisphosphonate is prescribed to treat excessive bone resorption in osteoporotic patients. However, its use is associated with potential adverse effects such as medication-related osteone
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