Seurat more cells A.2

<strong>seurat v3 object</strong> <br> <strong>ASSAYS:</strong> ADT: Antibody expression data RNA: mRNA expression data <br> <strong>DIMENSIONALITY REDUCTION</strong> projAML: Data was projected on the main AML dataset from Cohorts A and B. pca: pca computed on the 2000 most variable features umapSimple: umap computed from first 15 principal components <br> <strong>METADATA</strong> patient: Patient ct: Projected cell type (Triana et al., 2021) ct_simple: Simplified projected celltype batch: Cells come either from total bone marrow or CD34+ enrichment using either FACS or MACS seurat_clusters: unsupervised clusters obtained running the standard Seurat workflow proj_cluster: Projected cluster from main AML dataset leukemia_prob: CloneTracer leukemia probability status: Binarized status (healthy, leukemic, unsure) clonal_probability: CloneTracer clonal probability clone: Binarized clone dormancy_score: score assessing the dormancy of cells based on Zhang 2021 and Cabezas-Wallscheid 2017 gene lists.**Seurat v3 对象（Seurat v3 object）** **实验测定（ASSAYS）：** ADT：抗体表达数据（Antibody expression data）；RNA：信使RNA（mRNA）表达数据 **降维（DIMENSIONALITY REDUCTION）：** projAML：将数据投影自队列A与队列B的核心急性髓系白血病（AML）数据集；pca：基于2000个最高变异特征计算得到的主成分分析（PCA）；umapSimple：基于前15个主成分计算得到的均匀流形近似与投影（UMAP） **元数据（METADATA）：** patient：患者信息；ct：预测细胞类型（Triana等，2021）；ct_simple：简化版预测细胞类型；batch：细胞样本来源为全骨髓，或通过荧光激活细胞分选（FACS）、磁激活细胞分选（MACS）进行CD34+富集的样本；seurat_clusters：通过标准Seurat流程得到的无监督聚类结果；proj_cluster：核心AML数据集的投影聚类结果；leukemia_prob：CloneTracer算法计算的白血病概率；status：二分类状态（健康、白血病、不确定）；clonal_probability：CloneTracer算法计算的克隆概率；clone：二分类克隆信息；dormancy_score：基于Zhang等2021年与Cabezas-Wallscheid等2017年的基因列表，评估细胞休眠状态的评分。