Hepatic niche leads to aggressive NK-cell leukemia proliferation

We report the transcriptomic profiles of liver-tropic and spleen-tropic ANKL cells obtained from patient-derived xenograft (PDX) mouse. We also report the transcriptomic profiles of liver niche collected from healthy mice or PDX mice. Overall design: mRNA profiles of ANKL cells and mouse liver niche本研究报道了从患者来源异种移植（PDX）小鼠中分离得到的嗜肝性与嗜脾性ANKL细胞的转录组谱，同时还报道了从健康小鼠及PDX小鼠中采集的肝脏微环境的转录组谱。整体实验设计：ANKL细胞与小鼠肝脏微环境的mRNA转录谱。