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Supporting data for: CGREF1, A NOVEL HEPATOKINE REGULATED BY CREB-H, PROMOTES INSULIN RESISTANCE AND OBESITY BY SUPPRESSING GLUCOSE UPTAKE IN WHITE ADIPOSE TISSUE

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Figshare2022-05-26 更新2026-04-28 收录
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Transcription factor cAMP-responsive element binding protein H (CREB-H) is known to regulate many metabolism genes. Cell growth regulator with EF-hand domain 1 (CGREF1) has been identified as a new target of CREB-H. The supporting data of this thesis primarily records evidence of the regulation and function of CGREF1 captured in cell line and mouse models. Types of data in this dataset include 1) .xlsx files that can be viewed in any compatible versions of Microsoft Excel. 2) .jpeg files that can be viewed using 'Photos' in Windows or equivalent in Mac systems. 3) .pzf files that can be viewed using GraphPad Prism softwares.

转录因子cAMP应答元件结合蛋白H(CREB-H)可调控大量代谢相关基因,含EF手结构域的细胞生长调控因子1(CGREF1)已被鉴定为CREB-H的新型靶基因。本论文的支撑数据主要收录了在细胞系与小鼠模型中获取的CGREF1调控机制与功能相关实验证据。本数据集包含以下三类文件:1) 可通过任意兼容版本的Microsoft Excel(微软Excel)打开的.xlsx格式文件;2) 可使用Windows系统“照片”应用或Mac系统等效工具查看的.jpeg(JPEG)格式文件;3) 可通过GraphPad Prism软件读取的.pzf格式文件。

创建时间:
2022-05-26
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