Nucleotide sequences for all MDA5-producing species were obtained from UniProt and aligned using AliView. AliView identified 83 stop codons in the human sequence, which were removed using a Python scr
Pre-curation sequences. A fasta file containing the initial set of nucleotide sequences that was filtered through selection of robust clades and other steps (see methods and legend for File S4 above)
These files contain the trimmed Illumina short reads used to produce our hybrid assemblies. Reads were trimmed by Trimmomatic with trims HEADCROP:10 and SLIDINGWINDOW:4:20.
