Proteomic profiling of PDI-deficient mouse liver

A proteomics analysis with quantitative tandem mass tag mass spectrometry (TMT-MS) was performed to screen for altered hepatocyte proteins in the livers of PDI-deficient versus control mice.本研究采用定量串联质量标签质谱（TMT-MS）开展蛋白质组学分析，旨在筛选PDI缺陷小鼠与对照小鼠肝脏中存在表达差异的肝细胞蛋白。