Table S1 - Reduced Syncytin-1 Expression Levels in Placental Syndromes Correlates with Epigenetic Hypermethylation of the ERVW-1 Promoter Region

Methylation pattern of isolated trophoblasts. Methylation pattern of all 22 CpGs of isolated trophoblasts from control (n = 3), IUGR (n = 3), PE (n = 3), PE/IUGR (n = 3) and HELLP/IUGR (n = 2) placentae. CpG (−1) and CpG (−2) are located within the TSE and CpG 1 to 20 within the 5′LTR (Fig. 1A). Syncytin-1 gene expression is shown in molecules/ngcDNA. p (DOC)分离滋养层细胞的甲基化谱。本数据集涵盖对照组（n=3）、宫内生长受限（intrauterine growth restriction, IUGR）组（n=3）、子痫前期（preeclampsia, PE）组（n=3）、子痫前期合并宫内生长受限（PE/IUGR）组（n=3）以及HELLP综合征合并宫内生长受限（HELLP/IUGR）组（n=2）的胎盘来源分离滋养层细胞的全部22个CpG位点的甲基化谱。其中CpG(-1)与CpG(-2)定位于TSE区域，CpG 1至20则位于5′LTR区域（见图1A）。Syncytin-1基因的表达水平以molecules/ng cDNA为单位进行展示。p值（DOC）