Association of 10 SNPs on 9p22 with abnormal TVU screening results.

Per allele odds ratios obtained with an additive model restricted to the Caucasian population for the association of 9p22 SNPs with abnormal screening results are shown. Cases are women with suspicious screening results; controls are women with normal or non-suspicious screening results. Worst TVU results indicate abnormal TVU results at any screen during the 4-year follow-up. First TVU results indicate abnormal TVU results at the first screen a woman participated in. Incident TVU results are abnormal results among women that were normal or non-suspicious at the first screening. An asterisk indicates p-values lower than 0.005, the significance level after conservative Bonferroni correction.本研究展示了针对高加索人群（Caucasian population）采用加性模型（additive model）计算得到的、与9p22号单核苷酸多态性（Single Nucleotide Polymorphism, SNPs）和筛查结果异常相关的每等位基因优势比（allele odds ratios）。病例组为筛查结果可疑的女性，对照组为筛查结果正常或无可疑异常的女性。最差经阴道超声（Transvaginal Ultrasound, TVU）结果指4年随访期间任意一次筛查中出现的TVU异常结果；首次TVU结果指女性参与首次筛查时的TVU异常结果；新发TVU结果指首次筛查结果正常或无可疑异常的女性中出现的TVU异常结果。星号代表P值低于0.005，该阈值为经保守邦费罗尼（Bonferroni）校正后的显著性水平。