We interrogated the genome-wide occupancy of histone modifications and RNA polymerase II at several stages of an mouse embryonic stem cell to cardiomyocyte directed differentiation protocol. These fou

NIAID Data Ecosystem50

ATAC-Seq based chromatin accessibilty profile of MPPs from mice treated with MV130 or its excipient

训练免疫机制

干细胞染色质可及性

MV130 is an inactivated polybacterial mucosal vaccine that confers protection to patients against recurrent respiratory infections, including those of viral etiology. We showed that MV130 induces lon

NIAID Data Ecosystem40

ATAC-Seq profiles in hematopoietic stem cells treated with estradiol (E2).

表观遗传学

干细胞染色质可及性

ATAC-Seq was conducted to identify the regulome of hematopoietic stem cells. More specifically, we interrogated the effects of E2 on regions of accessible chromatin in HSCs.

NIAID Data Ecosystem50

ATAC-seq of uncultured CD112high and CD112low long-term(LT) human hematopoietic stem cells (HSC) from umbilical cord blood. ATAC-seq of uncultured CD112high and CD112low long-term(LT) human hematopoietic stem cells (HSC) from umbilical cord blood

干细胞染色质可及性

脐带血干细胞亚群

We performed ATAC-sequencing to elucidate the chromatin accessibility that underlie the differential in vitro priming and regeneration phenotypes of CD112high and CD112low LT-HSC. Therefore, we prospe

NIAID Data Ecosystem40

ATAC-seq of sorted cells at day 7.5 of cardiac differentiation from human embryonic stem cells

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