Genome-wide chromatin and gene expression profiling during memory formation and maintenance in adult mice. [Data Record 10: DEEs and DEGs]

<b>DESCRIPTION</b><br>This data record contains tables of differentially expressed genes (DEG) and exons (DEE), where each table contains comparisons between the conditions naive and context (N-C) and naive and context-shock (N-CS) for each time point (1h or 4w) and tissue (CA1 or ACC).<br><br><b>TABLES</b><br>DEG tables<br>Columns "ensemblID", "gene_name" and "description" refer to the ENSEMBL ID, gene symbol and gene description, respectively. Columns "chromosome", "start", "end" and "strand" indicate the position of the gene (with strand being "1" for positive strand or "-1" for negative strand). Column "biotype" refers to the type of gene (protein-coding, antisense, non-coding etc.). Finally, column "baseMean" refers to the mean expression of the gene in all samples, column "log2FoldChange" refers to the log2 fold change between the samples in the different conditions, and columns "pvlaue" and "padj" refer to the raw and Benjamini-Hochberg-adjusted p-values, respectively.<br>DEE tables<br>Column "ensemblID" still refers to the ENSEMBL gene ID, but some genes may appear multiple times, as they contain multiple exons, and the column "exonID" indicates the exon number in the gene. Columns “pvalue”, “padj”, “meanBase” and “log2FoldChange” correspond to the same columns in the DEG tables (with the exception of “meanBase”, which is equivalent to “baseMean” in the DEG tables).<br><br><b>DATA GENERATION</b><br>The code used to do differential expression analyses of genes and exons can be found in Figshare (https://dx.doi.org/10.6084/m9.figshare.3146749).<br><br><b>数据集说明</b><br>本数据集包含差异表达基因（differentially expressed genes, DEG）与差异表达外显子（differentially expressed exons, DEE）的分析表格，每张表格针对每个时间点（1h或4w）与组织（CA1或ACC），分别开展了未处理组与情境组（N-C）、未处理组与情境-电击组（N-CS）的组间比较。<br><br><b>表格说明</b><br>差异表达基因（DEG）表格<br>列"ensemblID"、"gene_name"与"description"分别对应ENSEMBL基因ID、基因符号与基因功能描述；列"chromosome"、"start"、"end"与"strand"用于标注基因的基因组位置（其中链信息：正链为"1"，负链为"-1"）；列"biotype"表示基因的生物类型（如蛋白编码、反义转录、非编码RNA等）。列"baseMean"为所有样本中该基因的平均表达量；列"log2FoldChange"为不同条件下样本间的对数2倍表达变化值；列"pvalue"（原文笔误为pvlaue）与"padj"分别代表原始P值与经Benjamini-Hochberg校正后的P值。<br>差异表达外显子（DEE）表格<br>列"ensemblID"仍对应ENSEMBL基因ID，但由于部分基因包含多个外显子，此类基因会在表格中多次出现；列"exonID"用于标注该外显子在对应基因中的编号。列"pvalue"、"padj"、"meanBase"与"log2FoldChange"的含义与DEG表格中的对应列一致（仅"meanBase"等价于DEG表格中的"baseMean"）。<br><br><b>数据生成</b><br>用于开展基因与外显子差异表达分析的代码可在Figshare平台获取（链接：https://dx.doi.org/10.6084/m9.figshare.3146749）。