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Sec6 negatively regulates antiviral innate immunity by degrading cGAS via the p53-Bax-caspase3 signaling axis

Name: Sec6 negatively regulates antiviral innate immunity by degrading cGAS via the p53-Bax-caspase3 signaling axis
Creator: Shandong Normal University
Published: 2026-01-21T23:26:31+08:00

integrated proteome resources2026-02-07 收录

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蛋白质信号通路

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0015182000 数据链接链接失效反馈

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资源简介：

Sec6 negatively regulates antiviral innate immunity by degrading cGAS via the p53-Bax-caspase3 signaling axis

应用场景：

提供机构：

Shandong Normal University

创建时间：

2026-01-21

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抗菌肽表达调控

Antimicrobial peptides that contribute to innate immunity are among the most important protective measures against infection in many organisms. Several substances are known to regulate the expression

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Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses

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To identify new regulators of antiviral innate immunity, we completed the first genome-wide gene silencing screen assessing the transcriptional response at the interferon-β (IFNB1) promoter following

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Additional file 7 of Nitrogen limitation causes a seismic shift in redox state and phosphorylation of proteins implicated in carbon flux and lipidome remodeling in Rhodotorula toruloides

蛋白质信号通路

代谢调控

Additional file 7. Select annotations for proteins involved in TOR, AMPK, calcium, MAPK, PI3K–Akt, and cAMP signaling pathways as well as corresponding differential expression data (global and PTMs) a

DataCite Commons2025-07-22 更新40

Table_2_C. elegans orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB.xlsx

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转录因子信号通路

In recent years, transcription factors of the Microphthalmia-TFE (MiT) family, including TFEB and TFE3 in mammals and HLH-30 in Caenorhabditis elegans, have emerged as important regulators of innate i

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Sec6 negatively regulates antiviral innate immunity by degrading cGAS via the p53-Bax-caspase3 signaling axis

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