Neural basis of adolescent THC-induced potentiation of opioid responses later in life - cFos Sample Images

cFos samples from the brains used in our study. Each .tif file can be viewed in ImageJ to scroll through 3D sections centered in four different regions: Globus Pallidus externus (GPe), prelimbic area (PL), hippocampus, and midline group of the dorsal thalamus. These regions were selected to represent a wide sample of different tissues that might show different trends in over or undercounting of cFos-labeled cells. The files with ".count.tif" show the cells marked by ClearMap. Resampled versions of the whole brain cfos signal are also included as "*.cfos_resampled.tif"本研究所用大脑组织的cFos样本。每个.tif格式文件均可通过ImageJ打开，用于滚动浏览以四个不同脑区为中心的三维切片：苍白球外侧部（Globus Pallidus externus, GPe）、前边缘皮层区（prelimbic area, PL）、海马体以及背侧丘脑中线核团。选取上述脑区作为样本，旨在覆盖多样的组织类型，这些组织在cFos标记细胞的计数偏差（偏高或偏低）上可能呈现不同趋势。后缀为.count.tif的文件展示了经ClearMap标记的细胞。此外，本数据集还包含全脑cFos信号的重采样版本，文件格式为*.cfos_resampled.tif。