IHC Figure 1 Model 1 Treated Photomicrographs

The first set of photomicrographs provided depict the lungs from mice bearing human breast cancer cell line xenografts subjected to DAB+ immune-histochemistry using antibodies to either anti-human high molecular weight cytokeratin (MDA-MB-468 cells, model 1) or anti-human Vimentin (MDA-MB-231 cells, model 2), a technique that was used to quantify metastatic deposits in the lungs.本次提供的首批光镜照片，展示了携带人乳腺癌细胞系异种移植物的小鼠肺部组织。该样本经二氨基联苯胺（DAB）增强免疫组织化学染色处理，所用抗体分别靶向抗人高分子量细胞角蛋白（MDA-MB-468细胞，模型1）与抗人波形蛋白（MDA-MB-231细胞，模型2）；该染色技术可用于量化肺部的肿瘤转移灶。