A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (Pregnancy Datasets). Homo sapiens

Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions. Overall design: Pregnancy (25 condition, 20 control, 45 total)开发一种兼具成本效益与实用性的靶向转录指纹检测（targeted transcriptional fingerprinting assay, TFA），用于监测人类血液转录组中鉴定出的多样化免疫应答谱。该检测依托基于全基因组范围转录本丰度变异构建的模块化转录谱，所用数据源自16种免疫状态下近1000名受试者的血液样本。实验整体设计：妊娠相关队列（25例病例组、20例对照组，总计45例样本）