Loss or gain of methylation (LOM or GOM, respectively: >10% difference from median).

Number (and percentage) of observations are displayed in the relevant groups. The chi-square test (3×2; df = 2) was performed to test for significant differences between MZ and DZ twins (see Table S2 for other cut-off values for loss or gain of methylation).各相关组别均列出了观测值的数量及其占比。本研究采用3×2列联表卡方检验（自由度df=2），以检验同卵双生子（Monozygotic, MZ）与异卵双生子（Dizygotic, DZ）之间的显著性差异；有关甲基化缺失或增益的其他截断值，请见表S2。