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Effect of pemafibrate on gene expression under Th17 differentiation condition

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NIAID Data Ecosystem2026-05-02 收录
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To investigate the effect of pemafibrate to Th17 cells, we differentiated naive T cells under Th17 condition. We then performed gene expression profiling analysis using data obtained from RNA-seq of 2 groups at 48hr after polarization. Comparative gene expression profiling analysis of RNA-seq data for vehicle and pemafibrate-treated cells.

为探究培马贝特(pemafibrate)对辅助性T细胞17(Th17)的调控作用,我们在Th17极化条件下诱导初始T细胞(naive T cells)完成分化。 随后,我们获取极化诱导后48小时的两组样本的RNA测序(RNA-seq)数据,并以此开展基因表达谱分析。 本次分析针对溶剂对照组与培马贝特处理组细胞的RNA-seq数据,完成了比较基因表达谱分析。

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2024-12-20
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