To evaluate the premalignant potential of high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP). Patients diagnosed with monofocal HGPIN (mHGPIN), wides
Brca2 homozygous mutant prostates (Brca2F/F;PBCre4) have hyperplasia (Hyp) at 10–14 months and LG PIN at 15–20 months. Brca2 homozygous Trp53 heterozygous mutant prostates (Brca2F/F;Trp53F/+;PBCre4) h
Prostate cancer research has been predominantly focused on adult exposures and risk factors. However, because the prostate develops during gestation and early life, exposure to external factors, such
