The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RNA interference. Here we report the 3.2 Å crystal structure of Kluyveromyces Argonaute (KpAGO) fortuitously complexed w

NIAID Data Ecosystem50

Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Caenorhabditis elegans

microRNA

Argonaute蛋白

MicroRNAs are regulators of gene expression whose functions are critical for normal development and physiology. We have previously characterized mutations in a Caenorhabditis elegans microRNA-specific

NIAID Data Ecosystem30

Ternary RsAgo Complex with Guide RNA and Target DNA Containing A-A non-canonical pair at position 3

Argonaute蛋白

RNA识别机制

Ternary RsAgo Complex with Guide RNA and Target DNA Containing A-A non-canonical pair at position 3 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP

Protein Data Bank Japan2024-03-13 更新30

Ternary RsAgo Complex with Guide RNA and Target DNA Containing A-A non-canonical pair at position 3

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