Nickel-Catalyzed Stereoselective Arylboration of Unactivated Alkenes

A Ni-catalyzed method for arylboration is disclosed. The method allows for highly stereoselective arylboration of unactivated alkenes. The reactions utilize a simple Ni-catalyst and work with a broad range of alkenes and aryl bromides. The products represent useful intermediates for chemical synthesis due to the versatility of the C–B bond. Preliminary mechanistic details of the method are also disclosed.本研究公开了一种镍催化的芳基硼化反应方法。该方法可实现未活化烯烃的高立体选择性芳基硼化反应。反应采用简便的镍催化剂，可兼容多种烯烃与芳基溴底物。由于碳-硼键（C–B bond）具有优异的反应多功能性，其产物可作为化学合成中的实用中间体。本研究同时披露了该方法的初步机理研究细节。