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Androgen receptor DNA binding in response to different ligands across three prostate cancer cell lines

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NIAID Data Ecosystem2026-05-26 收录
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We performed AR ChIP-seq in LNCaP-AR, VCaP and CWR22PC cells in the presence of vehicle, androgen, or androgen plus antiandrogen. These three cell lines showed variable sensitivity to these drugs. To determine the effects of AR agonist (R1881 vs DHT) and antagonists (Bicalutamide vs MDV3100) on the AR cistrome across a panel of prostate cancer cell lines.

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2019-05-15
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