ENCORI

ENCORI（全称Encyclopedia of RNA Interactomes，原名starBase）是一个综合性的RNA相互作用数据库。该数据库由中山大学开发，整合了来自CLIP-seq、降解组测序和RNA-seq等多种高通量测序数据，提供了miRNA-mRNA、miRNA-lncRNA、RNA-RNA和RNA-蛋白质相互作用信息。它支持pan-cancer分析，并包含23个物种、超过2700个CLIP-seq数据集和32种癌症类型的基因表达数据。

ENCORI (full name: Encyclopedia of RNA Interactomes, formerly known as starBase) is a comprehensive RNA interaction database. Developed by Sun Yat-sen University, it integrates multiple high-throughput sequencing datasets including CLIP-seq, degradome sequencing and RNA-seq, and provides information on miRNA-mRNA, miRNA-lncRNA, RNA-RNA and RNA-protein interactions. It supports pan-cancer analysis, and contains data from 23 species, over 2700 CLIP-seq datasets and gene expression data across 32 cancer types.

搜集汇总

背景与挑战

背景概述

ENCORI/starBase是一个综合性RNA相互作用图谱，整合了通过rbsSeeker和rriScan工具从大量CLIP-seq数据中识别的高置信度RBP-RNA和RNA-RNA相互作用。该数据集涵盖Pan-Cancer分析、降解组测序数据，并提供API和可视化工具，用于研究非编码RNA、mRNA和RBP的调控机制与功能。