BRAF Kinase domain b3aC loop deletion mutant in complex with sorafenib
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BRAF Kinase domain b3aC loop deletion mutant in complex with sorafenib Descriptor: 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Serine/threonine-protein kinase B-raf Authors: Whalen, D.M, Foster, S.A, Ozen, A, Wongchenko, M, Yin, J, Schaefer, G, Mayfield, J, Chmielecki, J, Stephens, P, Albacker, L, Yan, Y, Song, K, Hatzivassiliou, G, Eigenbrot, C, Yu, C, Shaw, A.S, Manning, G, Skelton, N.J, Hymowitz, S.G, Malek, S. Deposit date: 2016-01-11 Release date: 2016-04-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.512 Å) Cite: Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell, 29, 2016
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2016-01-11
