OptADMET

OptADMET is the integrated chemical transformation rule platform covering 32 important ADMET properties, which provides multiple-property rules and lead optimization direction. OptADMET provides the ADMET profiles of all optimized molecules from the queried molecule and enables the prediction of desirable substructure transformations and subsequent validation of drug candidates.OptADMET是一款整合型化学转化规则平台，覆盖32种重要的ADMET（吸收、分布、代谢、排泄与毒性）属性，可提供多属性规则与先导化合物优化方向。该平台可输出基于查询分子优化得到的全部候选分子的ADMET特征谱，支持预测合意的子结构转化方案，并可对候选药物开展后续验证工作。