Crystal Structure of MEK1 kinase bound to GDC0973
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Crystal Structure of MEK1 kinase bound to GDC0973 Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Ultsch, M.H. Deposit date: 2013-07-10 Release date: 2013-08-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers. Nature, 501, 2013
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2013-07-10
