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Ni-Catalyzed Highly Chemo‑, Regio‑, and Enantioselective Decarboxylative Aldol Reaction of β,γ-Unsaturated α‑Ketoesters with β‑Ketoacids

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Figshare2016-02-13 更新2026-04-29 收录
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A novel Ni-catalyzed decarboxylative aldol reaction of β,γ-unsaturated α-ketoesters with β-ketoacids is reported. The reaction proceeds smoothly with high chemo-, regio-, and enantioselectivity. This protocol provides a convenient approach to access enantioenriched chiral tertiary alcohols.

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2016-02-13
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