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Structure of human PARG complexed with JA2-9

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Structure of human PARG complexed with JA2-9 Descriptor: 4-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)butanoic acid, Poly(ADP-ribose) glycohydrolase Authors: Stegeman, R.A, Jones, D.E, Ellenberger, T, Kim, I.K, Tainer, J.A. Deposit date: 2019-03-15 Release date: 2019-12-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nat Commun, 10, 2019

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2019-03-15
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