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Catalyst-Controlled Switch in Diastereoselectivities: Enantioselective Construction of Functionalized 3,4-Dihydro‑2<i>H</i>‑thiopyrano­[2,3‑<i>b</i>]­quinolines with Three Contiguous Stereocenters

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NIAID Data Ecosystem2026-03-10 收录
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A tandem Michael–Henry reaction of 2-mercapto­quinoline-3-carbaldehydes with nitroolefins using hydrogen-bonding-based cooperative organocatalysts for the highly diastereodivergent synthesis of chiral functionalized 3,4-dihydro-2H-thiopyrano­[2,3-b]­quinolines with three contiguous tertiary stereocenters has been developed.

创建时间:
2017-01-29
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