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Enantioselective Activation of Stable Carboxylate Esters as Enolate Equivalents <i>via</i> N-Heterocyclic Carbene Catalysts

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NIAID Data Ecosystem2026-03-07 收录
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The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines.

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2016-02-21
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