Statistical tests for adaptive evolution indicate positive selection at the SEP53 locus.

Analysis used the computer program CODEML of the PAML package to compare models assuming KA/KS<1.0 at all sites (M1a, M7, M8a) to models assuming KA/KS>1.0 at some sites. 2Δl is two times the difference in the log likelihood for the two models under comparison. *** indicates p<0.0001. The column ‘ω>1’ shows KA/KS in the category of sites estimated to be above 1.0 in the selection models (and in brackets the proportion of sites in that category).