Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors

Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors Descriptor: 1-[(3P)-3-(3-chloro-2-fluorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methylpiperidin-4-amine, Tyrosine-protein phosphatase non-receptor type 11 Authors: Tang, Y, Nguyen, V, Wilbur, J.D. Deposit date: 2023-06-23 Release date: 2023-10-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors. J.Med.Chem., 66, 2023