Increase in peritoneal monocytes in LDLr KO mice receiving ORP8 KO BM, but decrease in peritoneal foam cells.

Peritoneal leukocytes were isolated from ORP8 KO BM recipients and wild type BM recipients and counted using a hematology analyzer at 17 weeks after BMT and 9 weeks WTD feeding. A) No difference between treatment groups was found in the total number of peritoneal leukocytes. B) The amount of peritoneal lymphocytes did not differ between the groups. C) Similarly, there was no difference between the groups in the amount of neutrophils in the peritoneum. D) However, there was an increase in the percentage of peritoneal monocytes out of total leukocytes in the ORP8 KO BM recipients, but no difference in macrophage content (* P