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Structure of dually phosphorylated c-MET receptor kinase in complex with an MK-2461 analog

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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Structure of dually phosphorylated c-MET receptor kinase in complex with an MK-2461 analog Descriptor: Hepatocyte growth factor receptor, N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-{5-oxo-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}sulfuric diamide Authors: Soisson, S.M, Rickert, K, Patel, S.B, Munshi, S, Lumb, K.J. Deposit date: 2011-03-22 Release date: 2012-02-01 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for selective small molecule kinase inhibition of activated c-Met. J.Biol.Chem., 286, 2011

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2011-03-22
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