STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency

This dataset contains the original raw and analyzed data supporting the manuscript “STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency”. The study identifies STT3A as an essential regulator of the Wnt signaling pathway and a potential therapeutic target for RNF43-deficient cancers. Included data were generated from key experiments, including Wnt reporter assays (DDT), Western blotting (WB), and CRISPR screen, and other experiments central to the study