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Rh(III)-Catalyzed Oxidative Coupling of <i>N</i>-Aryl-2-aminopyridine with Alkynes and Alkenes

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NIAID Data Ecosystem2026-03-06 收录
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[RhCp*Cl2]2 (1−2 mol %) can catalyze the oxidative coupling of N-aryl-2-aminopyridines with alkynes and arylates to give N-(2-pyridyl)indoles and N-(2-pyridyl)quinolones, respectively, using Cu(OAc)2 as an oxidant. Coupling with styrenes gave mono- and/or disubstituted olefination products.

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2010-12-03
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