Crystal Structure of small molecule vinylsulfonamide 14 covalently bound to K-Ras G12C
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Crystal Structure of small molecule vinylsulfonamide 14 covalently bound to K-Ras G12C Descriptor: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, N-{1-[(2,4-dichlorophenoxy)acetyl]piperidin-4-yl}ethanesulfonamide Authors: Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. Deposit date: 2013-08-04 Release date: 2013-11-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.703 Å) Cite: K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
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2013-08-04
