Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation Descriptor: (2-hydroxyphenyl)(pyrrolidin-1-yl)methanethione, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Sun, Q, Burke, J.P, Phan, J, Burns, M.C, Olejniczak, E.T, Waterson, A.G, Lee, T, Rossanese, O.W, Fesik, S.W. Deposit date: 2012-04-17 Release date: 2012-05-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angew.Chem.Int.Ed.Engl., 51, 2012