CIRCLE-seq analyais for -175 site
收藏NIAID Data Ecosystem2026-05-01 收录
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Adenosine base editing to recreate the HPFH mutations is a promising approach to induce HbF. We used CIRCLE-seq to identify 682 potential off-target sites in purified DNA treated with Cas9 nuclease complexed to sgRNA targeting ?-globin -175 . Overall design: CIRCLE-seq was performed in HEK293T cells.
创建时间：
2024-01-03
