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Try off-target enrichement
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创建时间：
2020-05-19
相关数据集
Optimizing genome editing strategy by primer-extension-mediated sequencing
High specificity of e\ngineered nucleases ensures precise genome editing. Couple methods were developed to identify off-target sites of CRISPR/Cas9, but hardly any high-throughput sequencing method ca
NIAID Data Ecosystem60
Genome-wide Profiling of Adenine Base Editor Specificity by EndoV-seq. Homo sapiens
EndoV-seq utilizes Endonuclease V (EndoV) to nick the inosine (I)-containing DNA strand of genomic DNA that has been deaminated by ABE in vitro. The treated DNA is then whole-genome sequenced to ident
NIAID Data Ecosystem40
Number of GUIDE-seq datasets and identified digested sequences. The numbers in the parentheses include technical replicates.
Number of GUIDE-seq datasets and identified digested sequences. The numbers in the parentheses include technical replicates.
Figshare2025-07-18 更新60
Improving the sensitivity of in vivo CRISPR off-target detection through DNA repair inhibition. Homo sapiens and Mus musculus
Improving the sensitivity of in vivo CRISPR off-target detection through DNA repair inhibition
NIAID Data Ecosystem50
