TCMSP
收藏资源简介:
TCMSP is a unique systems pharmacology platform of Chinese herbal medicines that captures the relationships between drugs, targets and diseases. The database includes chemicals, targets and drug-target networks, and associated drug-target-disease networks, as well as pharmacokinetic properties for natural compounds involving oral bioavailability, drug-likeness,intestinal epithelial permeability, blood-brain-barrier, aqueous solubility and etc. This breakthrough has sparked a new interest in the search of candidate drugs in various types of traditional Chinese herbs.
中药系统药理学平台(TCMSP)是一款独具特色的针对中草药的系统药理学平台,可精准捕捉药物、靶点与疾病之间的相互关联。该数据库涵盖化学物质、靶点及药物-靶点网络,以及相关的药物-靶点-疾病网络,同时收录了天然化合物的多项药代动力学特性,包括口服生物利用度、类药性、肠上皮通透性、血脑屏障穿透性、水溶性等。这一突破性成果重新激发了学界针对各类中草药开展候选药物筛选研究的浓厚兴趣。



