Brain Vessel Annotated Dataset from IXI-MRA Dataset

This dataset contains manually annotated brain vessel segmentations from 100 subjects of the IXI-MRA dataset, created as part of the research described in "Semi-automatic annotation of brain vessels in magnetic resonance angiography images". The annotations were generated using a semi-automatic pipeline combining Frangi filtering with expert manual refinement. The annotations provide ground truth for brain vessel segmentation tasks and can be used for algorithm development, validation, and benchmarking. 

Using this dataset you have to cite all the following papers and resources:1. Bernadotte, A., Elfimov, N. & Menshikov, I. Semi-automatic annotation of brain vessels in magnetic resonance angiography images. Sci Data (2025). https://doi.org/10.1038/s41597-025-06354-12.  Bernadotte, A., Elfimov, N., & Menshikov, I. (2025). Brain Vessel Annotated Dataset from IXI-MRA Dataset (1.0) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.173932023. Bernadotte, A., Elfimov, N., & Menshikov, I. (2025). Code repository of the paper "Semi-automatic annotation of brain vessels in magnetic resonance angiography images" (1.0). Zenodo. https://doi.org/10.5281/zenodo.173919984. LevshAI Homepage: https://www.neurosputnik.com.5. Menshikov, I., Orlov, K. V., Berestov, V. & Bernadotte, A. Preoperative Personalized Vascular 3D Simulator of the Intelligent Robotic Ecosystem LevshAI for Endovascular Neurosurgery, 2023 9th International Conference on Automation, Robotics and Applications (ICARA), Abu Dhabi, United Arab Emirates, pp. 6–10, https://doi.org/10.1109/ICARA56516.2023.10125981 (2023).6. Menshikov, I. & Bernadotte, A. Intelligent Robotic Motion Copying System LevshAi for Neurosurgical Endovascular Operations with Haptic Feedback and Preoperative Personalized Simulation, 2022 IEEE International Conference on Cyborg and Bionic Systems (CBS), Wuhan, China, pp. 386–391, https://doi.org/10.1109/CBS55922.2023.10115398 (2023).7. Bernadotte, A. Cyber Security for Surgical Remote Intelligent Robotic Systems. 2023 9th International Conference on Automation, Robotics and Applications (ICARA), Abu Dhabi, United Arab Emirates, pp. 65–69, https://doi.org/10.1109/ICARA56516.2023.10126050 (2023).

This project uses TOF-MRA images from the **IXI Dataset** (Imperial College London): https://brain-development.org/ixi-dataset/The original IXI data are released under the **CC BY-SA 3.0** license: https://creativecommons.org/licenses/by-sa/3.0/

We do not redistribute the original IXI images or any imaging derivatives in this repository. To reproduce our results, please download the IXI MRA data from the official IXI website and follow the original license terms.