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Processed editing efficiency data

Figshare2020-06-12 更新2026-04-28 收录

基因编辑效率

CRISPR碱基编辑

数据链接：

https://figshare.com/articles/dataset/Processed_editing_efficiency_data/10673816 数据链接链接失效反馈

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资源简介：

CSVs containing designed sgRNA-target sites and base editing outcomes across multiple replicates.

应用场景：

创建时间：

2020-06-12

CRISPR-Cas9sgRNA设计

基因编辑效率

Variable activity across different single guide RNAs (sgRNAs) remains a significant limitation of the CRISPR/Cas9 system. We have identified molecular features that influence sgRNA stability, activity

NIAID Data Ecosystem60

Generating Un1Cas12f1-ABE via RNA-Protein Recruitment Modules

CRISPR碱基编辑

基因编辑工程优化

Optimization of the Un1Cas12f1-ABE constructs, sgRNA scaffold, and deaminase.

NIAID Data Ecosystem40

Additional file 2 of Increased prime edit rates in KCNQ2 and SCN1A via single nicking all-in-one plasmids

基因编辑效率

癫痫相关基因

Additional file 2: Table S1. Individual data values of all data represented in this manuscript.

Figshare2023-07-14 更新30

Highly efficient CRISPR-mediated base editing for the gut Bacteroides spp. with pnCasBS-CBE

肠道菌群基因编辑

CRISPR碱基编辑

We constructed a pnCasBS-CBE system for base editing in the Bacteroides thetaiotaomicron to expand their genetic toolkit, which can efficiently convert a C:G to a T:A in the genome. As a functional pr

NIAID Data Ecosystem40

Homo sapiens and zebrafish Targeted Locus (Loci)

CRISPR-Cpf1

基因编辑效率

We find that pre-crRNAs comprising a full-length direct repeat (full-DR-crRNA) sequence with specific stem-loop G-C base substitutions exhibit increased editing efficiencies compared with the standard

NIAID Data Ecosystem30

Processed editing efficiency data

资源简介：

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