aAll strains listed are isogenic in the E134 background (see Materials and Methods). bThe details of the human POLG mutations and the associated disease can be found at the Human DNA polymerase γ muta

NIAID Data Ecosystem30

Unveiling the Secrets of Exercise: Decoding Exosomal Molecular Patterns in Humans During Exercise Using Metabolomic and Lipidomic Screening and Advanced Computational Analysis.

运动生理分子机制

外泌体脂质组学

The main objective of this project was to conduct a detailed analysis of EVs isolated from cerebrospinal fluid (CSF) and serum, as well as whole CSF, and plasma obtained from young, healthy individual

Figshare2025-03-11 更新20

Arabidopsis thaliana Uracil-DNA-Glycosylase mitochondrial mutation accumulation study

线粒体DNA修复

DNA断裂修复机制

Substitution rates in plant mitochondrial genes are extremely low, indicating strong selective pressure as well as efficient repair. Plant mitochondria possess base excision repair pathways, however,

NIAID Data Ecosystem60

Acute Aerobic Exercise Alters PBMC microRNA Expression: Insights into Sport- and Sex-Specific Variations

运动生理分子机制

耐力运动

Studying microRNAs in the immune cells of athletes offers a novel perspective on the molecular regulation of immune function and recovery, potentially uncovering strategies to enhance performance and

NIAID Data Ecosystem20

Exercise-induced mitochondrial translocation of p53 repairs mitochondrial DNA mutations

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