Catalytic Asymmetric Construction of Chiral Hydropyridazines <i>via</i> Conjugate Addition of <i>N</i>‑Monosubstituted Hydrazones to Enones
收藏NIAID Data Ecosystem2026-03-07 收录
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The first example of a highly enantioselective and scalable formal diaza–ene reaction between N-monosubstituted hydrazones and enones catalyzed by a simple chiral primary-second diamine salt has been developed. The catalytic process provides a highly practical and stereoselective synthetic method for chiral hydropyridazines.
创建时间:
2016-02-18



