Targeting transcriptional dependencies in cancer using a covalent CDK7 inhibitor
收藏官方服务:
资源简介:
Targeting transcriptional dependencies in cancer using a covalent CDK7 inhibitor
应用场景:
创建时间:
2013-12-23
相关数据集
Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer
Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dual specificity mitogen-activated protein kinase kina
Protein Data Bank Japan2024-07-10 更新60
First-line targ veted therapies of advanced hepatocellular carcinoma: A Bayesian network analysis of randomized controlled trials
Purpose A variety of targeted drug were developed and proved effective and safe in clinical trials. Our study aims to compare the efficacies and safety of different targeted drugs in advanced hepatoce
NIAID Data Ecosystem50
Table S2 from Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer
Disruption of the enzymatic activities of the transcription factor TFIIH by the small molecules Triptolide (TPL) or THZ1 could be used against cancer. Here, we used the MCF10A-ErSrc oncogenesis model
Figshare2020-06-01 更新30
Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system
Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p
NIAID Data Ecosystem60
Crystal structure of PRMT5:MEP50 in complex with MTA and TNG462
Crystal structure of PRMT5:MEP50 in complex with MTA and TNG462 Descriptor: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ... Authors: Whittington, D.A. Deposit date: 2025-01-31 Relea
Protein Data Bank Japan2025-03-19 更新30



