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CRISPR-mediated base editing in the genome with cjCBEmax and cjABE8e
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创建时间:
2022-08-05
相关数据集
Homo sapiens Genome sequencing. Homo sapiens
Recently, base editors, composed of cytidine deaminase, Cas9 nickase (nCas9), and uracil DNA glycosylase inhibitor (UGI), have recently been developed to substitute a C at a target site with T without
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CRISPR base editing of cis-regulatory elements enables target gene perturbations
CRISPR technology has demonstrated broad utility for controlling target gene expression. However, there remains a need for strategies capable of modulating expression via the precise editing of non-co
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Single CRISPR base editors to induce simultaneous C-to-T and A-to-G mutations
High-throughput sequencing data of CRISPR base editing assays in human cells
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Highly efficient CRISPR-mediated base editing for the gut Bacteroides spp. with pnCasBS-CBE
We constructed a pnCasBS-CBE system for base editing in the Bacteroides thetaiotaomicron to expand their genetic toolkit, which can efficiently convert a C:G to a T:A in the genome. As a functional pr
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Table_1_Highly Efficient CRISPR-Mediated Base Editing in Sinorhizobium meliloti.DOCX
Rhizobia are widespread gram-negative soil bacteria and indispensable symbiotic partners of leguminous plants that facilitate the most highly efficient biological nitrogen fixation in nature. Although
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