Neonatal rat cardiomyocytes (NRCMs) were isolated and cultured. Subsequently, NRCMs were treated with the agonist of Hydroxy-carboxylic Acid Receptor 1 (HCAR1), 3Cl-HBA (40 μM for 48 h) or DMSO as con

Alliance of Genome Resources10

RNA-seq of ppp1r13l knockdown in neonatal mice cardiomyocytes and lipopolysaccharide stimulation kinetics transcriptome

心肌细胞转录组

炎症机制

A novel ppp1r13l sequence variation causes dilated cardiomyopathy and cardiac inflammation. In this experiment we knocked down IASPP (protein product of ppp1r13l) in cardiomyocytes and exposed them to

NIAID Data Ecosystem00

RNA-sequencing (RNA-seq) of induced pluripotent stem cells (iPSC) and iPSC-derived astrocytes from control and Parkinson's disease patients carrying LRRK2 G2019S point mutation

帕金森病分子机制

iPSC分化

Purpose: The goal of this study is to compare the NGS-derived from transcriptome profiling (RNA-seq) of human iPSC, human iPSC-derived astrocytes from control and Parkinson’s disease LRRK2 G2019S, and

NIAID Data Ecosystem10

RNAseq of cultured neonatal rat ventricular cardiomyocytes treated with siRNA for Btg1 and Btg2 knockdown.

心肌细胞转录组

Btg基因敲低效应

Total RNA was isolated from n=3 culture wells per siRNA treatment group, from 6 independent primary neonatal rat cardiomyocyte isolations. RNA was pooled to obtain n=3 independent samples per siRNA tr

Alliance of Genome Resources00

Transcriptome of human iPSC-derived cardiomyocytes. null

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